Complete a unique challenge based on an historic scenario - The yellow fever outbreak. It is 1853, and an uncontrollable outbreak of yellow fever has occurred in New Orleans. Inhabitants of several nearby cities are also getting infected, and there are serious fears that the disease will spread to more cities, if measures are not taken in time.

StoryThe situation is compounded by the fact that a railroad does not exist in the region, and it is very difficult to quickly deliver medicines to the cities. Build your own railroad network to swiftly supply medicines across the region, and help scientists to find a vaccine in time to save more people from getting infected. The Yellow Fever DLC also contains additional five unique player portraits for multiplayer sessions.