Comforting and soothing, they provide a gentle continuous cooling effect for up to 8 hours helping you through your migraine. Kool 'n' Soothe Migraine is non-medicinal so safe to use with pain relief medication to maximise your relief. For best results Kool 'n' Soothe should be used at the first signs of migraine/ headache. Kool 'n' Soothe Migraine is safe to use during pregnancy. Kool 'n' Soothe Migraine can also be used during the hot summer months to cool and refresh. 8 hour effect Immediate cooling relief for migraine Comfort & soothing Non-medicinal KooL 'n' Soothe Migraine are soft gel sheets designed to provide immediate cooling relief to the severe discomfort associated with migraine and headaches.